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QubesOS is built on the principle of isolation, and GPUs aren’t designed to meet the strict isolation requirements QubesOS demands because they prioritize performance instead.

Nix is great for keeping your system clean and your sanity slightly intact. But thanks to how QubesOS handles templates and persistence, it’s not plug-and-play.

After this guide, you will be able to:

• replace apt or pacman with the nixpkgs package repository, even if you don’t care about declarativity
• use home-manager to set up all your configs and apps declaratively with just one config file and use it on any machine
• use any nixpkgs package one time only and without bloat, fix dependency hell and weird dependencies